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What Are the Early Signs of Dementia in Adults With Intellectual and Developmental Disabilities (IDD) as Observed by Family Caregivers?

Christina Marsack-Topolewski, PhD, LMSW

July 15, 2025

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Question

What are the early signs of dementia in adults with intellectual and developmental disabilities (IDD) as observed by family caregivers?

Answer

In a qualitative study of family caregivers supporting adults with IDD, five early indicators emerged that signaled the possible onset of dementia. These signs, while not clinical diagnoses on their own, provided vital context-sensitive insights grounded in daily lived experience. The first category, behavioral changes, involved new or intensified behaviors such as aggression or compulsivity that were inconsistent with the person’s prior baseline. These were often the earliest signs caregivers noticed and interpreted as a significant shift.

The second group, physical changes impacting function, included noticeable declines in mobility, increased fatigue, or difficulties performing routine tasks. These changes disrupted daily rhythms and were often reported before cognitive symptoms were formally recognized. Mood changes—including irritability, sadness, anxiety, or social withdrawal—were also frequently mentioned. These shifts, initially subtle, became more pronounced over time and often accompanied other functional or behavioral changes.

Memory-related concerns, particularly around procedural and short-term memory, formed a fourth category. Caregivers described lapses in task execution and the inability to retain recent information, which was especially concerning when long-established routines were forgotten. Lastly, atypical behaviors, such as dishonesty or stealing—behaviors starkly inconsistent with the individual's lifelong patterns—served as significant red flags. These changes were deeply unsettling for caregivers and often prompted further evaluation.

Collectively, these caregiver observations highlight how dementia may uniquely manifest in adults with IDD, requiring a nuanced and relational understanding that goes beyond standard diagnostic tools. Listening to caregivers’ insights is essential for timely identification and support.

This Ask the Expert is an edited excerpt from the course, Understanding And Supporting Adults With Intellectual And Developmental Disabilities With Cognitive Decline And Regressive Illnesspresented by Christina Marsack-Topolewski, PhD, LMSW. 


christina marsack topolewski

Christina Marsack-Topolewski, PhD, LMSW

Christina Marsack-Topolewski, LMSW, PhD, is a licensed social worker and an Associate Professor of Social Work at Eastern Michigan University. She received her bachelor of science in Special Education from Wayne State University, a master’s degree in Social Work from the University of Michigan, and her PhD in Social Work with a dual title in Gerontology from Wayne State University. She has 20 years of experience supporting individuals with intellectual and developmental disabilities and their family caregivers. Dr. Marsack-Topolewski has worked as a professor, clinical therapist, teacher, consultant, and speaker. She has published over 80 research articles in scholarly journals and encyclopedias regarding individuals with disabilities, family caregiving, aging, and dementia. Dr. Marsack-Topolewski has been the lead principal investigator on multiple grant-funded programs tailoring services for individuals with disabilities, older adults, and chronic illnesses. She is an appointed board member of the U.S. National Task Group (NTG) on Intellectual Disability and Dementia Practices. Dr. Marsack-Topolewski’s research has been featured on National Public Radio (NPR) and ABC News Detroit. Over the past five years, she testified before members of the Michigan Legislature to advocate for new laws that protect against the exploitation and abuse of adults with disabilities. The first of these house bills was signed into law in Michigan in December 2023. In 2024, she received the Ronald W. Collins Distinguished Research Award for Research Excellence. In addition, she received the Arc of Oakland County’s Advocacy Hall of Fame Award in 2024.


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